Translating Advanced Cancer Research into Personalized, Passionate Treatment.

Saint John’s Cancer Institute (formerly John Wayne Cancer Institute) is a cancer research institute dedicated to the understanding, diagnosis, and innovative treatment of cancer in order to eliminate patient suffering and prolong survival.

Medical Services

Urology & Urologic Oncology

We specialize in advanced robotic urologic procedures in combination with the newest therapeutic drugs as well as multiple clinical trials urologic cancer and disorders.

Melanoma, Skin & Soft Tissue Tumors

Our team of doctors and scientists are world leaders in melanoma research, therapeutic immunology, and innovative surgical approaches for skin and soft tissue cancers.

Endocrine Tumors & Disorders

Our experts offer a ‘one-stop shop’ for benign and malignant thyroid, parathyroid, adrenal, pituitary, and bone disorders that is complimented by clinical and translational research.

Breast Surgery & Oncology

Our Breast center offers a one-stop, comprehensive, multidisciplinary clinic for an array of supportive services to complement any breast health conditions.

Minimally Invasive Chest Surgery & Thoracic Surgical Oncology

We have the largest experience in the world using video-assisted thoracic surgical (VATS) lobectomy for lung cancer and treat all aspects of chest diseases.

Gastrointestinal & Hepatobiliary Tumors

We treat benign disease to advanced cancers of the colon, rectum, stomach, esophagus, pancreas and liver with a team of surgeons, oncologists, and radiation therapists.

Gynecologic Oncology

As leaders in the treatment of ovarian, uterine, cervical, vaginal and vulvar cancer, we specialize in providing personalized care to help you beat your cancer.

Translational Research Departments

Working side by side with our doctors, our researchers develop and apply new tests and therapies for cancer that are quickly introduced into the clinics.

Brain Tumors & Neuroscience

Our dedicated teams of specialists, state-of-the-art facilities and leading-edge treatment provides comprehensive care for patients with a wide spectrum of neurological and cranial disorders.